A small, randomized clinical trial at UC San Diego School of Medicine found that a single intravenous dose of a century-old drug called suramin produced measurable, but transient, improvement of core symptoms of autism spectrum disorder (ASD). But more broadly, the trial findings support the “Cell Danger Response theory,” which posits that autism and other…

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Autism spectrum disorder (ASD) is a group of developmental disabilities that can cause significant social, communication and behavioral challenges. Global prevalence of autism has increased twenty- to thirty-fold since the earliest studies 40–50 years ago. Just-published CDC data shows an estimated prevalence of 1 in 68 children affected by an autism spectrum disorder. ASD occurs…

James Coplan, MD, Developmental Pediatrician, describes some of the underlying neuropsychological deficits in children with ASD (cognitive rigidity, dysregulation of attention, arousal, sleep, and sensory processing), and explains how these underlying deficits lead to maladaptive behaviors such as insistence on sameness, perseveration, impulsivity, hyperactivity, agitation, aggressive or self-injurious behavior, poor sleep, and abnormalities of sensory…

In case you weren’t aware, Autism Spectrum Disorder (or ASD) affects 1 in every 68 children, and are much more commonly diagnosed in boys. Some studies show that boys are four times more likely than girls to have an ASD, but new research suggests that it may appear differently in girls, and therefore go undiagnosed…